Person

Jun Lin

Professor | Animal Science
Overview

I am a molecular microbiologist with training in infectious disease and immunology. My research program is primarily focused on molecular mechanisms of bacterial pathogenesis and antimicrobial resistance, which would reveal potential targets for development of novel intervention strategies and diagnostic tools against pathogens important in animal health and food safety. My expertise and experience also uniquely position my research program to emphasize translational projects that have a direct and tangible impact on the sustainability of animal production and public health.

My laboratory has a strong “One Health” emphasis on the interface of livestock, wildlife, environment, and human health. Due to this focus, I also have established multidisciplinary collaborations with the scientists from US and other countries (e.g. Japan, China, Ireland, and Northern Ireland).

Ongoing research projects in my laboratory include 1) Molecular mechanisms regulating membrane asymmetry of Gram-negative bacteria,; 2) Enterobactin-based immune intervention to control Gram-negative pathogens; 3) Microplastics and nanoplastics: novel analytical tool development and health effects; 4) Development of novel non-antibiotic approaches for mitigation of antimicrobial resistance in food animals; and 5) pathobiology and epidemiology of the emerging human pathogens Escherichia albertii in food animals and wildlife.

Research Focus

Infectious diseases with emphasis on molecular mechanisms of pathogenesis and antimicrobial resistance of zoonotic bacterial pathogens

Functional microbiome

Development of alternatives to antibiotics

Teaching Focus

Microbial Pathogenesis

Antimicrobial Resistance

Molecular Techniques

One Health

Courses
Below are courses taught during the current or past three academic years. Consult Timetable for the most current listing of courses and instructor(s).
ANSC 519 - Techniques in Molecular Biology
3 credit hour(s)

Conventional and modern techniques for DNA cloning and manipulation, mRNA expression and analysis, protein expression and analysis, various omics techniques, and bioinformatics tools. Labs will include comprehensive DNA cloning procedure, recombinant protein construction/purification as well as SDS-PAGE/immunoblotting analysis, real-time RT-PCR, and use of software for common genomics and bioinformatics analyses.

Contact Hour Distribution: 2 hours lecture and 2 hours lab.
Recommended Background: A good understanding of the basic knowledge in biochemistry, molecular biology, and microbiology at the college level, equivalent to BCMB 401 or BCMB 402, or above.
Registration Restriction(s): Minimum student level – graduate or permission of instructor.

ANSC 621 - Advanced Topics in Animal Physiology
1 - 4 credit hours

Recent advances and concepts, research techniques, current problems.

Repeatability: May be repeated. Maximum 6 hours.
Registration Restriction(s): Minimum student level – graduate.

Picture of Jun Lin
344 Brehm Animal Science Building
2506 River Dr
Knoxville, TN 37996-4574
Education and Training
  • PhD, Animal Science, Ohio State University, 1998
  • MS, Molecular Microbiology and Immunology, Fudan University, 1994
  • BS, Microbiology, General, Fudan University, 1991

Jun Lin

Professor | Animal Science
Picture of Jun Lin image
344 Brehm Animal Science Building
2506 River Dr
Knoxville, TN 37996-4574
Education and Training
  • PhD, Animal Science, Ohio State University, 1998
  • MS, Molecular Microbiology and Immunology, Fudan University, 1994
  • BS, Microbiology, General, Fudan University, 1991
Overview

I am a molecular microbiologist with training in infectious disease and immunology. My research program is primarily focused on molecular mechanisms of bacterial pathogenesis and antimicrobial resistance, which would reveal potential targets for development of novel intervention strategies and diagnostic tools against pathogens important in animal health and food safety. My expertise and experience also uniquely position my research program to emphasize translational projects that have a direct and tangible impact on the sustainability of animal production and public health.

My laboratory has a strong “One Health” emphasis on the interface of livestock, wildlife, environment, and human health. Due to this focus, I also have established multidisciplinary collaborations with the scientists from US and other countries (e.g. Japan, China, Ireland, and Northern Ireland).

Ongoing research projects in my laboratory include 1) Molecular mechanisms regulating membrane asymmetry of Gram-negative bacteria,; 2) Enterobactin-based immune intervention to control Gram-negative pathogens; 3) Microplastics and nanoplastics: novel analytical tool development and health effects; 4) Development of novel non-antibiotic approaches for mitigation of antimicrobial resistance in food animals; and 5) pathobiology and epidemiology of the emerging human pathogens Escherichia albertii in food animals and wildlife.

Research Focus

Infectious diseases with emphasis on molecular mechanisms of pathogenesis and antimicrobial resistance of zoonotic bacterial pathogens

Functional microbiome

Development of alternatives to antibiotics

Teaching Focus

Microbial Pathogenesis

Antimicrobial Resistance

Molecular Techniques

One Health

Courses
Below are courses taught during the current or past three academic years. Consult Timetable for the most current listing of courses and instructor(s).
ANSC 519 - Techniques in Molecular Biology
3 credit hour(s)

Conventional and modern techniques for DNA cloning and manipulation, mRNA expression and analysis, protein expression and analysis, various omics techniques, and bioinformatics tools. Labs will include comprehensive DNA cloning procedure, recombinant protein construction/purification as well as SDS-PAGE/immunoblotting analysis, real-time RT-PCR, and use of software for common genomics and bioinformatics analyses.

Contact Hour Distribution: 2 hours lecture and 2 hours lab.
Recommended Background: A good understanding of the basic knowledge in biochemistry, molecular biology, and microbiology at the college level, equivalent to BCMB 401 or BCMB 402, or above.
Registration Restriction(s): Minimum student level – graduate or permission of instructor.

ANSC 621 - Advanced Topics in Animal Physiology
1 - 4 credit hours

Recent advances and concepts, research techniques, current problems.

Repeatability: May be repeated. Maximum 6 hours.
Registration Restriction(s): Minimum student level – graduate.